We conducted an activation likelihood estimation (ALE) meta-analysis to quantitatively review the existing working memory (WM) training studies that investigated neural activation changes both in healthy individuals and patients with schizophrenia. ALE analysis of studies in healthy individuals indicates a widespread distribution of activation changes with WM training in the frontal and parietal regions, especially the dorsolateral prefrontal cortex, the medial frontal cortex and the precuneus, as well as subcortical regions such as the insula and the striatum. WM training is also accompanied by activation changes in patients with schizophrenia, mainly in the dorsolateral prefrontal cortex, the precuneus and the fusiform gyrus. Our results demonstrate that WM training is accompanied by changes in neural activation patterns in healthy individuals, which may provide the basis for understanding neuroplastic changes in patients with schizophrenia. PMID:26032579 Hospital executives and claims adjusters are experienced in analyzing and handling malpractice claims and settlement negotiations on behalf of the hospital You need someone to represent your interest. Protecting Your Claim: What Every Personal Injury Plaintiff Should Know, presented at�Brain Injury Association of New York State Annual Conference. June 2015 Registered Professional Engineer, States of Ohio and New York 1968-present Dental Lawyer Companies McKownville 44704.
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